Science Letter
December 30, 2008
PHYSICS;
Research by D.B. Saakian and colleagues in physics provides new insights
According to recent research from Yerevan, Armenia, "We introduce an
alternative way to study molecular evolution within well-established
Hamilton-Jacobi formalism, showing that for a broad class of fitness
landscapes it is possible to derive dynamics analytically within the
1/N accuracy, where N is the genome length. For a smooth and monotonic
fitness function this approach gives two dynamical phases: smooth
dynamics and discontinuous dynamics."
"The latter phase arises naturally with no explicite singular fitness
function, counterintuitively. The Hamilton-Jacobi method yields
straightforward analytical results for the models that utilize fitness
as a function of Hamming distance from a reference genome sequence,"
wrote D.B. Saakian and colleagues (see also Physics).
The researchers concluded: "We also show the way in which this method
gives dynamical phase structure for multipeak fitness."
Saakian and colleagues published their study in Physical Review E
(Dynamics of the Eigen and the Crow-Kimura models for molecular
evolution. Physical Review E, 2008;78(4 Part 1):1908).
For additional information, contact D.B. Saakian, Yerevan Physics
Institute, Alikhanian Bros St. 2, Yerevan 375036, Armenia.
Publisher contact information for the journal Physical Review E is:
American Physical Society, One Physics Ellipse, College Pk, MD
20740-3844, USA.
From: Emil Lazarian | Ararat NewsPress
Disclaimer: This article was contributed and translated into English by Emil Lazarian. While we strive for quality, the views and accuracy of the content remain the responsibility of the contributor. Please verify all facts independently before reposting or citing.
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